Key result
Off-pump coronary artery bypass grafting was safely performed as a standard surgical revascularization strategy, demonstrating an operative mortality of 0.8% and a 7-year overall survival rate of 85.5% in a single-center cohort.
Why the study?
Does isolated off-pump CABG improve long-term survival and reduce major adverse cardiac and cerebrovascular events in patients requiring surgical revascularization?
Does isolated off-pump CABG improve long-term survival and reduce major adverse cardiac and cerebrovascular events in patients requiring surgical revascularization?
Isolated off-pump CABG can be safely performed as a standard surgical revascularization strategy, demonstrating low operative mortality and acceptable long-term clinical outcomes.
May support off-pump CABG in experienced centers; leaves open randomized confirmation of long-term superiority versus on-pump.
Percutaneous coronary intervention is the first choice for treatment of a simple coronary artery lesion due to the progress of coronary stents in recent years. In contrast, patients with multiple, diffuse and severely diseased coronary lesions must undergo coronary artery bypass grafting (CABG); these patients also often have multiple comorbidities and severe preoperative conditions. Off-pump CABG has been developed to lessen the complications caused by the use of cardiopulmonary bypass, as cardiopulmonary bypass is considered more risky in patients with multiple atherosclerotic diseases. The necessity for off-pump CABG may increase in the future, as it is expected that patients with more severe atherosclerotic disease will be candidates for CABG with further progress of coronary stent techniques. This review aimed to investigate the safety and efficacy of off-pump CABG as a standard revascularization strategy.
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Fukui et al. (2016) conducted a review in Coronary artery disease (n=1,265). Off-pump coronary artery bypass grafting was evaluated on 7-year freedom from all-cause death. Off-pump coronary artery bypass grafting was safely performed as a standard surgical revascularization strategy, demonstrating an operative mortality of 0.8% and a 7-year overall survival rate of 85.5% in a single-center cohort.
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