Key result
Survivors of sudden cardiac death without coronary artery disease had significantly lower total spectral heart rate variability over 24 hours compared to healthy controls (38 vs 48 ms; p<0.05).
Why the study?
Is heart rate variability decreased in survivors of sudden cardiac death not associated with coronary artery disease compared to healthy controls?
Case-Control (n=20)
Is heart rate variability decreased in survivors of sudden cardiac death not associated with coronary artery disease compared to healthy controls?
Absolute Event Rate: 38% vs 48%
p-value: p=< 0.05
Survivors of sudden cardiac death without coronary artery disease exhibit decreased heart rate variability, suggesting abnormal autonomic influence on the heart.
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May reflect autonomic dysfunction in sudden cardiac death survivors without coronary disease; hypothesis-generating case-control data leaves open prospective validation.
Fei et al. (1994) conducted a case-control in Aborted sudden cardiac death not associated with coronary artery disease (n=20). Survivor of sudden cardiac death not associated with coronary artery disease vs. Healthy controls was evaluated on Total spectral heart rate variability over 24 hours (ms) (p=< 0.05). Survivors of sudden cardiac death without coronary artery disease had significantly lower total spectral heart rate variability over 24 hours compared to healthy controls (38 vs 48 ms; p<0.05).
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