Key result
A random urine protein/creatinine ratio of 0.5 mg/mg showed 96% sensitivity and 96% specificity for diagnosing significant 24-hour proteinuria in hypertensive pregnant women.
Why the study?
Does the protein/creatinine ratio in a single random urine sample accurately predict significant 24-hour proteinuria in hypertensive pregnant women?
Population
47 hypertensive pregnant women seen at the Maternity of the University Hospital of Porto Alegre
Comparison
Protein/creatinine ratio measured in a single… vs Protein determination in 24-hour urine
Design
Cross-sectional
Authors
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May support spot urine protein/creatinine ratio as alternative to 24-h collection in hypertensive pregnancies; leaves open prospective validation before routine use.
Cross-Sectional (n=47)
No
Does the protein/creatinine ratio in a single random urine sample accurately predict significant 24-hour proteinuria in hypertensive pregnant women?
A random urine protein/creatinine ratio of 0.5 mg/mg is highly predictive of significant 24-hour proteinuria in hypertensive pregnant women, offering a simpler alternative to 24-hour urine collection.
Ramos et al. (1999) conducted a cross-sectional in Systemic arterial hypertension in pregnancy (n=47). Protein/creatinine ratio in a single random urine sample vs. 24-h proteinuria was evaluated on Diagnosis of significant proteinuria (≥ 300 mg in 24 h). A random urine protein/creatinine ratio of 0.5 mg/mg showed 96% sensitivity and 96% specificity for diagnosing significant 24-hour proteinuria in hypertensive pregnant women.
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