Key result
Acute ischemic stroke was associated with significantly elevated plasma NT-proBNP concentrations at admission compared with controls (129.9 vs 90.8 fmol/mL, p<0.05).
Why the study?
Are NT-proBNP levels elevated in patients with acute ischemic stroke compared to controls?
Case-Control (n=60)
Are NT-proBNP levels elevated in patients with acute ischemic stroke compared to controls?
Absolute Event Rate: 129.9% vs 90.8%
p-value: p=<0.05
NT-proBNP levels are significantly elevated in the acute phase of ischemic stroke and remain elevated at day 6, particularly in cardioembolic infarctions, suggesting neurohumoral activation.
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May reflect neurohumoral activation in acute stroke; leaves open biomarker utility for etiology or prognosis.
Giannakoulas et al. (2005) conducted a case-control in Acute ischemic stroke (n=60). Acute ischemic stroke vs. Controls was evaluated on Plasma NT-proBNP concentrations at admission (p=<0.05). Acute ischemic stroke was associated with significantly elevated plasma NT-proBNP concentrations at admission compared with controls (129.9 vs 90.8 fmol/mL, p<0.05).
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