What question did this study set out to answer?

To investigate the emergence of suicidal preoccupation in patients treated with fluoxetine.

Emergence of intense suicidal preoccupation during fluoxetine treatment

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Case study reveals intense suicidal thoughts in depressed patients after fluoxetine, suggesting need for caution.

To investigate the emergence of suicidal preoccupation in patients treated with fluoxetine.
Six depressed patients observed for changes in suicidal ideation during fluoxetine treatment.
Patients were free of serious suicidal ideation prior to treatment and monitored for 2-7 weeks post-initiation.
Assessment of suicidal thoughts continued post-discontinuation for 3 days to 3 months.
All six patients developed intense suicidal preoccupation after 2-7 weeks on fluoxetine.
This suicidal state persisted for varying durations after stopping fluoxetine, from 3 days to 3 months.
None had prior experiences of similar suicidal preoccupation with other psychotropic medications.

Teicher et al. (1990) studied this question.

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