Why the study?
Does angiotensin II stimulate prostaglandin E production in cultured human umbilical vein endothelial cells?
Population
Cultured human umbilical vein endothelial cells
Design
Preclinical
Authors
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No direct clinical implications from cell culture; leaves open in vivo relevance for vascular tone and permeability.
Does angiotensin II stimulate prostaglandin E production in cultured human umbilical vein endothelial cells?
Angiotensin II stimulates prostaglandin E production in cultured human vascular endothelium, highlighting a potential mechanism for local control of vascular permeability and tone.
Gimbrone et al. (1975) studied this question.