Key result
Ginsenosides offer non-toxic protection against chemotherapy-induced cardiotoxicity by targeting various cellular pathways.
Why the study?
Current strategies for managing chemotherapy-induced cardiotoxicity have limited efficacy and cause detrimental side effects, necessitating novel and potent non-toxic therapies targeting cellular pathways.
Do ginsenosides protect against chemotherapy-induced cardiotoxicity in the cardio-oncology field?
Design
Comprehensive review
Authors
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May support adjunctive use in cardio-oncology; leaves open confirmation via randomized trials.
Do ginsenosides protect against chemotherapy-induced cardiotoxicity in the cardio-oncology field?
Ginsenosides offer a promising natural therapeutic approach to mitigate chemotherapy-induced cardiotoxicity by targeting oxidative stress, inflammation, and apoptosis pathways.
Adib-Hajbagheri et al. (2025) conducted a review in Chemotherapy-induced cardiotoxicity. Ginsenosides was evaluated. Ginsenosides present non-toxic and efficacious alternatives for addressing chemotherapy-induced side effects, including cardiotoxicity, by targeting various cellular pathways.
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