Why the study?
The impact of right ventricular apical pacing on very long-term cardiac prognosis in patients with sick sinus syndrome and preserved or mildly reduced left ventricular ejection fraction is little known.
Does a high burden of right ventricular apical pacing (≥50%) increase cardiovascular events in pacemaker recipients with sick sinus syndrome and LVEF >35%?
Population
532 consecutive pacemaker recipients with SSS and LVEF >35%
Comparison
Mean %VP ≥50% vs <50%
Design
Retrospective cohort study
Follow-up
Mean 13.4±7.0 years
Authors
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High RV pacing burden was not independently associated with events; leaves open whether minimizing pacing improves outcomes after adjusting for AF and comorbidities.
Does a high burden of right ventricular apical pacing (≥50%) increase cardiovascular events in pacemaker recipients with sick sinus syndrome and LVEF >35%?
In patients with sick sinus syndrome and LVEF >35%, a high burden of right ventricular apical pacing (≥50%) is not an independent predictor of cardiovascular events after adjusting for age, atrial fibrillation, and structural heart disease.
Nakasuka et al. (2019) studied this question.
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