Key result
Quadripolar left ventricular pacing configurations increased cardiac index by 29% versus 23% for unipolar-simulated configurations (P<0.05), and yielded a 90% CRT responder rate.
Why the study?
Does quadripolar pacing configuration improve hemodynamic response in patients implanted with a CRT device compared to unipolar-simulated and bipolar configurations?
Population
27 consecutive patients implanted with a CRT device with an LV quadripolar lead
Comparison
Quadripolar pacing configuration using an LV… vs Unipolar-simulated and bipolar pacing…
Design
Cohort
Follow-up
3-month
Authors
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* *Idea:* Quadripolar LV pacing may optimize hemodynamics.
Does quadripolar pacing configuration improve hemodynamic response in patients implanted with a CRT device compared to unipolar-simulated and bipolar configurations?
Absolute Event Rate: 29% vs 23%
p-value: p=<0.05
Quadripolar LV pacing configurations significantly improve hemodynamic response and CRT responder rates compared to unipolar and bipolar configurations.
Osca et al. (2014) studied Patients implanted with a CRT device with an LV quadripolar lead (n=27). Quadripolar pacing configuration vs. Unipolar-simulated and bipolar pacing configurations was evaluated on Increase in cardiac index in relation to reference (p=<0.05). Quadripolar left ventricular pacing configurations increased cardiac index by 29% versus 23% for unipolar-simulated configurations (P<0.05), and yielded a 90% CRT responder rate.
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