Why the study?
Does hypotension produced by halothane improve the balance of myocardial oxygen supply and demand compared to nitroprusside in open-chested dogs?
Population
6 open-chested dogs with healthy hearts and normal coronary anatomy
Comparison
Hypotension produced by halothane vs Hypotension produced by nitroprusside
Design
Preclinical
Authors
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Supports preserved energetics during induced hypotension in healthy canine hearts; leaves open translation to patients with coronary disease.
Does hypotension produced by halothane improve the balance of myocardial oxygen supply and demand compared to nitroprusside in open-chested dogs?
Hypotension induced by either nitroprusside or halothane does not impair myocardial energetics in healthy hearts with normal coronary anatomy.
CHAMBERLAIN et al. (1980) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: