Why the study?
Does halothane reduce myocardial ischemia compared to a combination of nitroprusside and propranolol in an experimental animal model of coronary occlusion?
Population
Experimental animal model of myocardial ischemia induced by temporary occlusion of the left-anterior…
Comparison
Halothane (1.1% end-tidal concentration) vs Combination of nitroprusside and propranolol
Design
Preclinical
Authors
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Halothane may reduce ischemia more in this animal model; leaves open translation to human perioperative care.
Does halothane reduce myocardial ischemia compared to a combination of nitroprusside and propranolol in an experimental animal model of coronary occlusion?
In an experimental animal model of myocardial ischemia, halothane provided a significantly greater reduction in ischemic ST-segment elevation compared to a hemodynamically matched combination of nitroprusside and propranolol.
Gerson et al. (1982) studied this question.
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