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March 10, 2009Hypertension

Influence of Adiposity and Physical Activity on Arterial Stiffness in Healthy Children

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Why the study?

Are adiposity and physical activity associated with arterial stiffness in healthy children?

Population

573 community-based healthy children, mean age 10.1±0.3 years, 51% boys.

Design

Cross-sectional

Authors

SSSatoru SakuragiIwakuni Medical CenterKAKatrina AbhayaratnaCanberra HospitalKGK. GravenmakerCanberra Hospital

Discussion

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Implication

Adiposity may mark early arterial changes in healthy children; leaves open whether interventions targeting body composition alter PWV.

Structured PICO

Are adiposity and physical activity associated with arterial stiffness in healthy children?

P
Population
573 community-based healthy children, mean age 10.1±0.3 years, 51% boys.
O
Outcome
Carotid-femoral pulse wave velocity (PWV)surrogate

Increased body mass and adiposity, along with decreased cardiorespiratory fitness, are associated with arterial stiffening in healthy prepubescent children.

Cite This Study

Sakuragi et al. (2009) studied this question.

synapsesocial.com/papers/6a22984e37cd05c4adcd3e03https://doi.org/10.1161/hypertensionaha.108.123364
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of age and aerobic capacity on arterial stiffness in healthy adults.1993 · 1,085 citations
  2. 2Overweight and Sympathetic Overactivity in Black Americans2001 · 112 citations
  3. 3Evidence for a Link Between Adipose Tissue Interleukin-6 Content and Serum C-Reactive Protein Concentrations in Obese Subjects1999 · 245 citations
  4. 4Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans2000 · 3,831 citations
  5. 5Determinants of Early Atherosclerosis in Obese Children and Adolescents2007 · 210 citations