Key result
Higher heart rate and waist-to-height ratio are linked to increased aortic stiffness in at-risk children.
Why the study?
Limited information is available on the respective features of cf-PWV and cr-PWV and their modulating factors in children and adolescents at increased cardiovascular risk.
Population
443 children and adolescents with elevated BP or excess body weight
Comparison
Mechanical properties of elastic (cf-PWV) vs muscular (cr-PWV) arteries
Design
Cross-sectional study
Authors
Loading...
May inform risk stratification in high-risk youth; hypothesis-generating for causal and interventional studies.
Cross-Sectional (n=443)
Odds Ratio: 1.07 (95% CI 1.04–1.1)
p-value: p=<0.001
In children and adolescents at increased cardiovascular risk, central obesity and blood pressure are associated with aortic stiffness, while heart rate and insulin resistance relate to upper limb vascular distensibility.
Genovesi et al. (2023) conducted a cross-sectional in Increased cardiovascular risk (elevated blood pressure or excess body weight) (n=443). Heart rate and waist-to-height ratio was evaluated on High cf-PWV (>95th percentile) (OR 1.07, 95% CI 1.04-1.10, p=<0.001). Heart rate (OR 1.07; 95% CI 1.04-1.10) and waist-to-height ratio (OR 1.06; 95% CI 1.0-1.13) were significant predictors of high aortic stiffness in children at increased cardiovascular risk.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: