Key result
Adiposity and its metabolic consequences were strongly and inversely associated with arterial distensibility in adolescents, even at BMI levels below those considered obese.
Why the study?
Do adiposity and metabolic disturbances reduce arterial distensibility in adolescents?
Population
471 British children aged 13 to 15 years, some of whom had previously been studied at ages 9 to 11 years
Design
Cohort
Follow-up
Up to approximately 4 years
Authors
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Adiposity may impair arterial distensibility even below obese BMI in teens; hypothesis-generating for prevention trials.
Observational (n=471)
Do adiposity and metabolic disturbances reduce arterial distensibility in adolescents?
Adiposity and its metabolic consequences are strongly associated with reduced arterial distensibility in adolescents, highlighting the need for early population-based prevention strategies.
Whincup et al. (2005) conducted an observational in Preclinical atherosclerosis (n=471). Adiposity and metabolic disturbances was evaluated on Brachial artery distensibility. Adiposity and its metabolic consequences were strongly and inversely associated with arterial distensibility in adolescents, even at BMI levels below those considered obese.