Key result
Type 2 diabetes was associated with a significantly higher aortic augmentation index compared to controls (136.1% vs 128.3%; P=0.006), indicating increased arterial stiffness.
Why the study?
Does Type 2 diabetes increase augmentation of aortic systolic pressure compared to controls?
Population
88 subjects with Type 2 diabetes and 85 control subjects
Comparison
Type 2 diabetes (observational exposure) vs Control subjects without Type 2 diabetes
Design
Case-control
Authors
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May indicate higher CV risk in type 2 diabetes; leaves open causal role of stiffness in outcomes.
Cross-Sectional (n=173)
Does Type 2 diabetes increase augmentation of aortic systolic pressure compared to controls?
Absolute Event Rate: 136.1% vs 128.3%
p-value: p=0.006
Type 2 diabetes is associated with increased arterial stiffness and an unfavorable ratio of myocardial perfusion to cardiac workload, particularly in men.
Brooks et al. (2001) conducted a cross-sectional in Type 2 diabetes (n=173). Type 2 diabetes vs. Controls was evaluated on aortic augmentation index (p=0.006). Type 2 diabetes was associated with a significantly higher aortic augmentation index compared to controls (136.1% vs 128.3%; P=0.006), indicating increased arterial stiffness.
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