Key result
In a mouse model of acute myocardial infarction, treatment with globular CTRP9 improved survival (P<0.05), restored cardiac function (P<0.05), and attenuated adverse remodeling (P<0.01).
Why the study?
Does CTRP9 improve survival and attenuate adverse cardiac remodeling after acute myocardial infarction in mice?
Does CTRP9 improve survival and attenuate adverse cardiac remodeling after acute myocardial infarction in mice?
p-value: p=<0.05
CTRP9 attenuates adverse cardiac remodeling and improves survival after acute myocardial infarction in a mouse model, largely via a PKA-dependent pathway.
No takes yet. Share an insight, caveat, or question.
Supports CTRP9 investigation post-MI; hypothesis-generating and requires validation before any clinical consideration.
Sun et al. (2013) studied Acute myocardial infarction. Globular CTRP9 vs. Saline (vehicle) was evaluated on Animal survival rate, cardiac function, and adverse remodeling (p=<0.05). In a mouse model of acute myocardial infarction, treatment with globular CTRP9 improved survival (P<0.05), restored cardiac function (P<0.05), and attenuated adverse remodeling (P<0.01).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: