Key result
Decreased plasma adiponectin levels independently correlated with impaired left ventricular longitudinal strain in asymptomatic hypertensive patients (β=-0.273, p=0.008).
Why the study?
Is decreased plasma adiponectin associated with impaired left ventricular longitudinal systolic function in asymptomatic hypertensive patients?
Cross-Sectional (n=118)
Is decreased plasma adiponectin associated with impaired left ventricular longitudinal systolic function in asymptomatic hypertensive patients?
Effect estimate: β=-0.273
p-value: p=0.008
Decreased plasma adiponectin is independently associated with impaired LV longitudinal systolic function and progression of LV hypertrophy in asymptomatic hypertensive patients.
The influence of plasma adiponectin levels on myocardial contractile function has not been fully examined. We aimed to investigate the relationship between three-directional systolic function and plasma adiponectin levels in asymptomatic hypertensive patients using two- dimensional speckle-tracking echocardiography. The study population consisted of 78 patients with hypertension and 40 healthy controls. Longitudinal strain was significantly reduced in all patients, including those without LV hypertrophy (p=0.009). In multiple-regression analysis, plasma adiponectin levels (β=-0.273, p=0.008) and LV mass index (β=0.458, p<0.001) independently correlated with LV longitudinal strain. Decreased plasma adiponectin concentrations were associated with the progression of LV hypertrophy with impaired LV longitudinal systolic function.
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Özkan et al. (2013) conducted a cross-sectional in Hypertension (n=118). Plasma adiponectin levels vs. Healthy controls was evaluated on Left ventricular longitudinal strain (β=-0.273, p=0.008). Decreased plasma adiponectin levels independently correlated with impaired left ventricular longitudinal strain in asymptomatic hypertensive patients (β=-0.273, p=0.008).
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