Key result
Plasma adiponectin concentration was significantly lower in hypertensive patients compared to normotensive patients (9.9 vs 12.9 μg/ml, p=0.019) and inversely correlated with LV mass index.
Why the study?
Is plasma adiponectin associated with left ventricular mass index and diastolic function in patients with and without hypertension?
Population
275 patients evaluated for plasma adiponectin, essential hypertension, left ventricular diastolic function…
Design
Cross-sectional
Authors
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Hypothesis-generating for adiponectin in hypertensive LV remodeling; should not yet change practice or guide therapy.
Cross-Sectional (n=275)
Is plasma adiponectin associated with left ventricular mass index and diastolic function in patients with and without hypertension?
Absolute Event Rate: 9.9% vs 12.9%
p-value: p=0.019
Decreased plasma adiponectin concentration is associated with the progression of left ventricular hypertrophy and diastolic dysfunction in hypertensive patients.
Hong et al. (2004) conducted a cross-sectional in Essential hypertension (n=275). Essential hypertension vs. Normotension was evaluated on Plasma adiponectin concentration (μg/ml) (p=0.019). Plasma adiponectin concentration was significantly lower in hypertensive patients compared to normotensive patients (9.9 vs 12.9 μg/ml, p=0.019) and inversely correlated with LV mass index.
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