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February 17, 2017Archives of Endocrinology and MetabolismOpen Access

Predictors of subclinical atherosclerosis evaluated by carotid intima-media thickness in asymptomatic young women with type 1 diabetes mellitus

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Population

45 asymptomatic young adult women with type 1 diabetes mellitus, mean age 36 ± 9 years, mean diabetes…

Design

Cross-sectional

Authors

RKRosane KupferInstituto Estadual de Diabetes e Endocrinologia Luiz CapriglioneMLManuella Rangel LarrúbiaPontifical Catholic University of Rio de JaneiroIBIsabela BussadeClínica Las Condes

Discussion

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Implication

May support risk stratification in young women with type 1 diabetes; leaves open whether targeting insulin resistance or obesity alters atherosclerosis progression.

Structured PICO

P
Population
45 asymptomatic young adult women with type 1 diabetes mellitus, mean age 36 ± 9 years, mean diabetes duration 18.1 ± 9.5 years.
O
Outcome
Carotid artery intima-media thickness (CIMT) and occurrence of carotid artery plaques evaluated by carotid Doppler ultrasoundsurrogate

In asymptomatic young women with type 1 diabetes, insulin resistance, central obesity, hypertension, and older age are significant predictors of subclinical atherosclerosis.

Cite This Study

Kupfer et al. (2017) studied this question.

synapsesocial.com/papers/6a22bfffd5ef0a743714e433https://doi.org/10.1590/2359-3997000000255
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