Key result
Unilateral renal arterial clipping in marmosets resulted in a transient renin-dependent hypertension, with blood pressure and plasma renin activity returning to control values within 10 weeks.
Authors
Loading...
Animal model shows transient clip hypertension; leaves open translation to human renovascular disease and chronic models.
Wood et al. (1986) studied Two-kidney, one clip (2K1C) renal hypertension. Unilateral renal arterial clipping (2K1C) vs. Control values was evaluated on Blood pressure (BP) and plasma renin activity (PRA). Unilateral renal arterial clipping in marmosets resulted in a transient renin-dependent hypertension, with blood pressure and plasma renin activity returning to control values within 10 weeks.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: