Key result
Among adults with chronic kidney disease, a 1-SD higher systolic blood pressure was strongly associated with incident end-stage renal disease (HR 1.67; 95% CI 1.43-1.96).
Why the study?
Which blood pressure index has the strongest association with end-stage renal disease risk in adults with chronic kidney disease?
Cohort (n=2,772)
Yes
Which blood pressure index has the strongest association with end-stage renal disease risk in adults with chronic kidney disease?
Hazard Ratio: 1.67 (95% CI 1.43–1.96)
Systolic blood pressure is the strongest predictor of incident end-stage renal disease among various blood pressure indexes in patients with chronic kidney disease.
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SBP should not yet guide ESRD risk management in CKD; leaves open whether targeting it improves outcomes.
Bell et al. (2012) conducted a cohort in Chronic kidney disease (n=2,772). Systolic blood pressure (SBP) vs. Other blood pressure indexes (DBP, PP, MAP) was evaluated on End-stage renal disease (ESRD) incidence (HR 1.67, 95% CI 1.43-1.96). Among adults with chronic kidney disease, a 1-SD higher systolic blood pressure was strongly associated with incident end-stage renal disease (HR 1.67; 95% CI 1.43-1.96).
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