Why the study?
Does oral testosterone undecanoate improve myocardial perfusion and vascular function in men with coronary heart disease and low plasma testosterone?
Population
22 men aged 40 to 75 years with angiographically proven CHD, low plasma testosterone, and normal…
Comparison
Oral testosterone undecanoate 80 mg twice daily… vs Identical matching placebo for 8 weeks.
Design
RCT, Randomly assigned in a crossover study design., Placebo-controlled…
Follow-up
8 weeks per treatment period
Authors
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Regional perfusion gains and stiffness reduction without global change advise against routine use; extends RCT evidence for targeted effects in hypogonadal CHD.
Does oral testosterone undecanoate improve myocardial perfusion and vascular function in men with coronary heart disease and low plasma testosterone?
Oral testosterone undecanoate had selective and modest enhancing effects on perfusion in myocardium supplied by unobstructed coronary arteries and decreased basal arterial stiffness in men with CHD and low testosterone.
Webb et al. (2007) studied this question.
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