What question did this study set out to answer?

The aim is to evaluate how the management of malignant hypertension affects survival rates, especially concerning renal function.

July 13, 1967New England Journal of Medicine

Management of Malignant Hypertension Complicated by Renal Insufficiency

View Full Paper

Ask AI

Bookmark

Why the study?

Does lowering of blood pressure improve survival in patients with malignant hypertension complicated by renal insufficiency?

Population

Patients with malignant hypertension complicated by renal insufficiency

Design

Cohort

Authors

JWJames W. WoodsNational Center for Biotechnology Information WBWilliam B. BlytheUniversity of North Carolina at Chapel Hill

Discussion

Member takes

Implication

BP lowering may improve survival in malignant hypertension with renal insufficiency; leaves open optimal targets and modern validation.

Key Points

The aim is to evaluate how the management of malignant hypertension affects survival rates, especially concerning renal function.
Study involved analysis of large patient series with malignant hypertension and renal insufficiency.
Evaluated treatment outcomes before and after the introduction of hypotensive drugs.
Prior to treatment, 79% to 90% of patients died within the first year of malignant hypertension.
In treated nonazotemic patients, one-year survival rate is reported at 85% and twelve-year survival at 38%.
Renal function at diagnosis significantly influences survival outcomes.

Structured PICO

Does lowering of blood pressure improve survival in patients with malignant hypertension complicated by renal insufficiency?

Population

Patients with malignant hypertension complicated by renal insufficiency

Intervention

Lowering of blood pressure (hypotensive drugs)

Outcome

Survival rate / length of survivalhard clinical

The study investigates the impact of blood pressure lowering on survival in patients with malignant hypertension and renal insufficiency.

Cite This Study

Woods et al. (1967) studied this question.

synapsesocial.com/papers/6a22e8da46d2b2b483f2e2b8 https://doi.org/10.1056/nejm196707132770201

View Full Paper

Ask AI

Bookmark

Management of Malignant Hypertension Complicated by Renal Insufficiency

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Management of Malignant Hypertension Complicated by Renal Insufficiency

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider