Key result
Elevated preoperative serum levels of BNP, NT-proBNP, and VEGF were associated with worse performance status, local invasion, distant metastasis, and shorter overall survival in clear cell RCC.
Why the study?
Are elevated preoperative serum levels of BNP and NT-proBNP associated with tumor progression and survival in patients with clear cell renal cell carcinoma?
Population
Patients with clear cell renal cell carcinoma (RCC) who underwent nephrectomy
Design
Cohort
Authors
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Elevated BNP/NT-proBNP may flag higher-risk clear cell RCC; leaves open added prognostic value beyond staging pending prospective validation.
Observational
Are elevated preoperative serum levels of BNP and NT-proBNP associated with tumor progression and survival in patients with clear cell renal cell carcinoma?
Preoperative serum levels of BNP and NT-proBNP are associated with tumor progression and worse overall survival in patients with clear cell renal cell carcinoma.
Kamai et al. (2018) conducted an observational in Clear cell renal cell carcinoma. Elevated preoperative serum levels of BNP and NT-proBNP was evaluated on Tumour progression and overall survival. Elevated preoperative serum levels of BNP, NT-proBNP, and VEGF were associated with worse performance status, local invasion, distant metastasis, and shorter overall survival in clear cell RCC.
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