Why the study?
Does a specific serum BNP cut-off accurately diagnose heart failure and predict survival in patients with chronic kidney disease presenting with dyspnea?
Population
182 patients with chronic kidney disease presenting with NYHA class II dyspnea. Mean age 60.3±13.4 years, 99…
Comparison
Serum brain natriuretic peptide measurement vs BNP level <858.5 pg/mL
Design
Cohort
Follow-up
mean 50.3±35.6 months
Authors
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May support higher BNP threshold for HF diagnosis in CKD dyspnea; hypothesis-generating and needs prospective validation.
Does a specific serum BNP cut-off accurately diagnose heart failure and predict survival in patients with chronic kidney disease presenting with dyspnea?
In patients with chronic kidney disease presenting with dyspnea, a higher BNP cut-off (858.5 pg/mL) is required to accurately diagnose heart failure and predict mortality compared to patients with normal renal function.
Yang et al. (2008) studied this question.
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