Key result
Graded upright bicycle exercise increased stroke volume by 26% and LV ejection fraction from 0.60 to 0.69 during mild exercise (P<0.01), with minimal changes at higher workloads.
Why the study?
How does graded upright bicycle exercise affect left ventricular volumes in healthy untrained men?
Population
7 healthy untrained men aged 21-30 years
Comparison
Graded upright bicycle exercise vs Rest (baseline)
Design
Other
Authors
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Caution against extrapolating to patients; leaves open mechanisms of SV augmentation in health versus disease.
Observational (n=7)
How does graded upright bicycle exercise affect left ventricular volumes in healthy untrained men?
Absolute Event Rate: 0.69% vs 0.6%
p-value: p=<0.01
In healthy untrained men, the most pronounced increases in stroke volume and ejection fraction occur during mild upright exercise, with minimal further changes at higher workloads despite increasing catecholamines.
Kelbæk et al. (1988) conducted an observational in Healthy (n=7). Graded upright bicycle exercise vs. Rest was evaluated on LV ejection fraction (p=<0.01). Graded upright bicycle exercise increased stroke volume by 26% and LV ejection fraction from 0.60 to 0.69 during mild exercise (P<0.01), with minimal changes at higher workloads.
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