Why the study?
Does upright exercise alter the volumetric responses of the right and left ventricles in normal subjects?
Population
9 normal subjects
Comparison
Upright exercise on a bicycle ergometer at 50%… vs Rest
Design
Cross-sectional
Key result
Upright exercise in normal subjects significantly increased stroke volume index from 40 to 59 ml/m2 (P<0.001) and right ventricular end-diastolic volume index from 82 to 95 ml/m2 (P=0.008).
Authors
Loading...
Supports Frank-Starling role in upright exercise SV for normals; leaves open translation to patients with heart disease.
Observational (n=9)
Does upright exercise alter the volumetric responses of the right and left ventricles in normal subjects?
Absolute Event Rate: 59% vs 40%
p-value: p=<0.001
Upright submaximal exercise augments stroke volume index through both the Frank-Starling mechanism and an increased contractile state in normal subjects.
Mahler et al. (1985) conducted an observational in Healthy (n=9). Upright exercise vs. Rest was evaluated on Stroke volume index (SVI) (p=<0.001). Upright exercise in normal subjects significantly increased stroke volume index from 40 to 59 ml/m2 (P<0.001) and right ventricular end-diastolic volume index from 82 to 95 ml/m2 (P=0.008).