Key result
Patients with alcoholic liver cirrhosis had an impaired haemodynamic response to exercise, with 45% vs 17% of controls showing an LVEF increase of ≤5% during physical stress (P<0.05).
Why the study?
Does alcoholic liver cirrhosis impair physical work capacity and cardiac function response to exercise compared to matched controls?
Case-Control (n=58)
Does alcoholic liver cirrhosis impair physical work capacity and cardiac function response to exercise compared to matched controls?
Absolute Event Rate: 45% vs 17%
p-value: p=<0.05
Patients with alcoholic liver cirrhosis exhibit reduced physical work capacity and an impaired cardiac functional response to physical stress compared to matched controls.
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Alerts clinicians to possible blunted cardiac reserve in alcoholic cirrhosis; case-control data leaves open prognostic and screening implications.
Kelbæk et al. (1987) conducted a case-control in Alcoholic liver cirrhosis (n=58). Alcoholic liver cirrhosis vs. Sex- and age-matched healthy controls was evaluated on Increase in left ventricular ejection fraction of ≤5% during exercise (p=<0.05). Patients with alcoholic liver cirrhosis had an impaired haemodynamic response to exercise, with 45% vs 17% of controls showing an LVEF increase of ≤5% during physical stress (P<0.05).
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