The Aminco-French pressure cell provides a rapid and effective method for human platelet homogenization with better organelle preservation than traditional pestle homogenization.
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No clinical data provided; leaves open any role for pressure-cell platelet homogenization in research or practice.
Summary A rapid effective method for platelet homogenization using a pressure cell is described. With this method, almost complete homogenization of human platelets occurred without excessive solubilization of enzymes as compared to a pestle homogenization procedure where there was incomplete homogenization. Electron microscopy of pressure homogenates and fractions revealed well preserved organelles.
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French et al. (1974) studied this question.
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