Key result
Blood fibrinogen level correlated with CAD severity (r=0.32) but not extent (r=0.14), and age was the only independent predictor of CAD severity and extent in multiple linear regression.
Why the study?
Does blood fibrinogen level independently predict the extent and severity of coronary artery disease in male patients with symptomatic CAD?
Population
91 male patients with symptomatic coronary artery disease (CAD) undergoing elective coronary angiography
Design
Cross-sectional
Authors
Loading...
Fibrinogen lacks independent association with CAD severity after adjustment; leaves open its biomarker utility in broader cohorts.
Cross-Sectional (n=91)
Does blood fibrinogen level independently predict the extent and severity of coronary artery disease in male patients with symptomatic CAD?
p-value: p=<0.05
Blood fibrinogen levels do not independently predict the extent or severity of coronary artery disease when accounting for other major risk factors like age.
McGill et al. (1990) conducted a cross-sectional in Coronary artery disease (n=91). Blood fibrinogen level was evaluated on Extent and severity of coronary artery disease (p=<0.05). Blood fibrinogen level correlated with CAD severity (r=0.32) but not extent (r=0.14), and age was the only independent predictor of CAD severity and extent in multiple linear regression.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: