Key result
Addition of maximum carotid IMT to conventional risk factors significantly improved the prediction ability for severe CAD requiring revascularization (AUC increased from 0.67 to 0.79; P=0.039).
Why the study?
Does carotid maximum IMT improve the identification of severe coronary artery disease in asymptomatic type 2 diabetic patients without a history of CAD?
Observational (n=333)
Does carotid maximum IMT improve the identification of severe coronary artery disease in asymptomatic type 2 diabetic patients without a history of CAD?
Effect estimate: AUC 0.79 vs 0.67
p-value: p=0.039
Carotid maximum IMT is a useful screening tool for identifying severe, asymptomatic coronary artery disease requiring revascularization in patients with type 2 diabetes.
No takes yet. Share an insight, caveat, or question.
Maximum carotid IMT may aid CAD prediction in asymptomatic T2D; hypothesis-generating and should not yet change practice.
Irie et al. (2013) conducted an observational in Asymptomatic type 2 diabetes without history of coronary artery disease (n=333). Carotid maximum intima-media thickness (IMT) vs. Conventional risk factors alone was evaluated on Severe CAD corresponding to treatment with revascularization (AUC 0.79 vs 0.67, p=0.039). Addition of maximum carotid IMT to conventional risk factors significantly improved the prediction ability for severe CAD requiring revascularization (AUC increased from 0.67 to 0.79; P=0.039).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: