Key result
The DD-ACE genotype adversely influences specific cardiovascular diseases in certain geographical areas and patient subgroups, though its overall impact is small and heterogeneous.
Why the study?
Does the DD-ACE genotype increase the risk of cardiovascular disease such as myocardial infarction?
Population
Patients evaluated for cardiovascular disease risk, specifically myocardial infarction and ischaemic heart…
Design
Systematic_review
Authors
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DD-ACE genotyping should not inform clinical risk stratification; leaves open targeted validation in geographic and subgroup-specific contexts.
Does the DD-ACE genotype increase the risk of cardiovascular disease such as myocardial infarction?
The DD-ACE genotype has a small, heterogeneous adverse effect on cardiovascular disease risk, likely dependent on geographic and subgroup factors.
Robert J. Butler (2000) conducted a review in Cardiovascular disease. DD-ACE genotype was evaluated. The DD-ACE genotype adversely influences specific cardiovascular diseases in certain geographical areas and patient subgroups, though its overall impact is small and heterogeneous.
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