Why the study?
Is the ACE DD genotype associated with an increased risk and extent of coronary artery disease?
Population
292 patients undergoing coronary angiography, including 196 with angiographically proven coronary artery…
Comparison
Presence of the angiotensin-I-converting enzyme… vs Controls without CAD and patients with…
Design
Case-control
Authors
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ACE DD genotype was associated with CAD presence and extent; leaves open its added value for clinical risk stratification.
Is the ACE DD genotype associated with an increased risk and extent of coronary artery disease?
The ACE DD genotype is a genetic risk factor for the presence and extent of coronary artery disease, particularly multivessel disease.
Sigusch et al. (1997) studied this question.
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