Key result
Impaired fibrinolytic activity is associated with an increased risk of postoperative thrombosis, but published evidence does not prove an association with symptomatic thrombosis.
Why the study?
Is impaired fibrinolytic activity associated with an increased risk of venous thromboembolism?
Systematic Review
Is impaired fibrinolytic activity associated with an increased risk of venous thromboembolism?
Impaired fibrinolytic activity is associated with postoperative venous thromboembolism, but evidence is lacking for a causal relationship or an association in general symptomatic thrombosis.
No takes yet. Share an insight, caveat, or question.
No proven link to symptomatic thrombosis cautions against routine testing; leaves open postoperative predictive value pending targeted trials.
Martin H. Prins (1991) conducted a systematic review in Venous thromboembolism. Impaired fibrinolytic activity was evaluated on Venous thromboembolism (symptomatic and postoperative thrombosis). Impaired fibrinolytic activity is associated with an increased risk of postoperative thrombosis, but published evidence does not prove an association with symptomatic thrombosis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: