Key result
Fibrinolytic variables including PAI-1, tPA, and euglobulin clot lysis times did not predict recurrent venous thrombosis over up to 3 years of follow-up.
Why the study?
Do fibrinolytic variables predict recurrent venous thrombosis in patients with a first episode of venous thromboembolism?
Cohort (n=303)
Do fibrinolytic variables predict recurrent venous thrombosis in patients with a first episode of venous thromboembolism?
Measuring fibrinolytic parameters in patients with venous thromboembolism does not predict recurrence and is not justified for modifying treatment.
No takes yet. Share an insight, caveat, or question.
Fibrinolytic testing does not predict recurrent VTE; leaves open whether alternative markers improve post-VTE risk stratification.
Patrassi et al. (2001) conducted a cohort in venous thromboembolism (n=303). Fibrinolytic variables (PAI-1, tPA, euglobulin clot lysis times) was evaluated on recurrent venous thrombosis. Fibrinolytic variables including PAI-1, tPA, and euglobulin clot lysis times did not predict recurrent venous thrombosis over up to 3 years of follow-up.
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