Why the study?
Does fibrinolytic response to venous occlusion correlate with DVT recurrence in patients with spontaneous or recurrent DVT?
Population
Patients with spontaneous or recurrent deep vein thrombosis without any known organic disease able to…
Design
Cohort
Authors
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May warrant t-PA testing to flag higher DVT recurrence risk; leaves open clinical utility pending prospective validation.
Does fibrinolytic response to venous occlusion correlate with DVT recurrence in patients with spontaneous or recurrent DVT?
A poor fibrinolytic response to venous occlusion occurs in 35% of DVT patients, and deficient t-PA release is associated with a higher incidence of DVT recurrence.
Juhan‐Vague et al. (1987) studied this question.
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