Key result
Pharmacologic management of acute and chronic heart failure in children relies on optimizing ventricular loading conditions, judicious use of inotropy, and promoting ventricular remodeling.
This review provides a pathophysiologic framework for the selection and titration of pharmacologic therapies in pediatric patients with acute and chronic heart failure.
Heart failure may result from a wide variety of causes and present with varying degrees of severity. In large part patients present with varying degrees of congestion and compromised cardiac output. In this review a pathophysiologic construct is provided to guide the pharmacologic management of acute heart failure that leads to decreased congestion and improved cardiac output. Pharmacologic therapies that are used to treat chronic heart failure are also highlighted and provide the framework for transitioning from acute to preventative pharmacologic strategies.
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Tume et al. (2016) conducted a review in Heart failure in children. Pharmacologic therapies was evaluated. Pharmacologic management of acute and chronic heart failure in children relies on optimizing ventricular loading conditions, judicious use of inotropy, and promoting ventricular remodeling.
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