Key result
Stimulation of afferent nerves evoked diverse postsynaptic responses in the nucleus tractus solitarius, which were not modified by lung inflation or respiratory cycle timing.
Population
Cats (in vivo model) studying neurones in the nucleus of the tractus solitarius (NTS)
Design
Preclinical
Authors
Loading...
No immediate clinical implications from this animal model; leaves open the downstream site of respiratory gating in baroreflex pathways.
Respiratory gating of the baroreceptor reflex does not occur via synaptic actions within the nucleus tractus solitarius, indicating these modifications must occur at later stages in the reflex pathway.
Mifflin et al. (1988) studied this question. Afferent nerve stimulation (carotid sinus, aortic, superior laryngeal, and vagal nerves) was evaluated on Postsynaptic responses in the nucleus of the tractus solitarius. Stimulation of afferent nerves evoked diverse postsynaptic responses in the nucleus tractus solitarius, which were not modified by lung inflation or respiratory cycle timing.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: