Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 1, 1998Journal of Neurophysiology

Convergence Properties of Solitary Tract Neurons Responsive to Cardiac Receptor Stimulation in the Anesthetized Cat

View Full Paper
Ask AI
Bookmark
Share

Population

Anesthetized, paralyzed, and artificially ventilated cats

Design

Preclinical

Authors

LSL Silva-CarvalhoUniversity of LisbonJPJulian F. R. PatonGeneral CardiologyIRIsabel RochaUniversidade Federal de Minas Gerais

Discussion

Loading...

Member takes

Implication

Remains preclinical in feline NTS; leaves open convergence effects on human cardiorespiratory reflexes.

Structured PICO

P
Population
Anesthetized (pentobarbitone sodium, 40 mg/kg), paralyzed, and artificially ventilated cats (78 NTS neurons recorded)
I
Intervention
Stimulation of cardiac receptors (veratridine 1-3 micrograms/kg), pulmonary C-fibers (phenylbiguanide 10-20 micrograms/kg), carotid body (CO2-saturated bicarbonate), carotid sinus (inflation), and electrical stimulation of vagal/carotid sinus nerves
O
Outcome
Convergence patterns and electrophysiological responses of NTS neuronssurrogate

The study demonstrates convergence of carotid chemoreceptor and pulmonary C-fiber afferent inputs, but not baroreceptor inputs, onto cardioreceptive NTS neurons in cats, suggesting a role in defensive or protective reflex control.

Cite This Study

Silva-Carvalho et al. (1998) studied this question.

synapsesocial.com/papers/6a7dbc15286d888403cda986https://doi.org/10.1152/jn.1998.79.5.2374
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Arterial chemoreceptor input to nucleus tractus solitarius1992 · 135 citations
  2. 2Responses of neurons in the nucleus tractus solitarius to stimulation of heart and lung receptors in the rat.1994 · 49 citations
  3. 3The location of cardiac vagal preganglionic motoneurones in the medulla of the cat.1976 · 249 citations
  4. 4IMPULSES IN VAGAL AFFERENT FIBRES FROM SPECIFIC PULMONARY DEFLATION RECEPTORS. THE RESPONSE OF THESE RECEPTORS TO PHENYL DIGUANIDE, POTATO STARCH, 5‐HYDROXYTRYPTAMINE AND NICOTINE, AND THEIR RÔLE IN RESPIRATORY AND CARDIOVASCULAR REFLEXES1955 · 187 citations
  5. 5Activation of cardiac vagal afferents in ischemia and reperfusion. Prostaglandins versus oxygen-derived free radicals.1994 · 82 citations