Why the study?
Is the M235T polymorphism of the angiotensinogen gene associated with hypertrophic cardiomyopathy in a South Indian population?
Is the M235T polymorphism of the angiotensinogen gene associated with hypertrophic cardiomyopathy in a South Indian population?
The T allele of the AGT gene is significantly associated with sporadic, but not familial, hypertrophic cardiomyopathy in a South Indian population.
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No immediate clinical implications for HCM; hypothesis-generating for sporadic disease mechanisms, needing replication.
Rao et al. (2010) studied this question.
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