Why the study?
Are angiotensinogen gene variants M235T and T174M associated with an increased risk of coronary heart disease or hypertension in the Indian population?
Population
431 subjects from the Indian population, comprising 131 healthy individuals, 141 angiographically verified…
Comparison
Presence of angiotensinogen gene variants M235T… vs Healthy individuals and absence of the specific…
Design
Case-control
Authors
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No association seen in this Indian case-control study; leaves open replication in larger, multi-ethnic cohorts before ruling out risk.
Are angiotensinogen gene variants M235T and T174M associated with an increased risk of coronary heart disease or hypertension in the Indian population?
The M235T and T174M variants of the angiotensinogen gene do not contribute to an increased risk of coronary heart disease or hypertension in the Indian population.
Nair et al. (2003) studied this question.
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