Why the study?
Does epinephrine alter coronary flow in isolated monkey hearts?
Population
Freshly isolated monkey hearts perfused with autogenous hirudinized blood diluted with Locke solution
Design
Preclinical
Authors
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Species differences in epinephrine coronary effects caution against rabbit models; leaves open human translation.
Does epinephrine alter coronary flow in isolated monkey hearts?
Epinephrine causes coronary vasoconstriction in monkeys, suggesting a similar physiological response in humans that differs from other mammals.
Barbour et al. (1915) studied this question.
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