Key result
A clinical prediction model using 8 predictors estimated the absolute 3-year risk of MACE after carotid endarterectomy with a C statistic of 0.69 (95% CI 0.64-0.73).
Why the study?
Can a clinical prediction rule accurately estimate the absolute 3-year risk of MACE after carotid endarterectomy?
Population
1138 consecutive patients who underwent carotid endarterectomy between 2002 and 2009
Design
Cohort
Follow-up
mean 2.28 (± 0.95) years
Authors
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May support post-CEA risk stratification; leaves open external validation before clinical use.
Cohort (n=1,138)
Can a clinical prediction rule accurately estimate the absolute 3-year risk of MACE after carotid endarterectomy?
Effect estimate: C statistic 0.69 (95% CI 0.64-0.73)
A newly developed clinical prediction model can stratify the 3-year risk of MACE after carotid endarterectomy to help optimize secondary prevention.
Lammeren et al. (2012) conducted a cohort in Carotid endarterectomy (n=1,138). Clinical prediction model was evaluated on Major adverse cardiovascular events (myocardial infarction, stroke, and cardiovascular death) (C statistic 0.69, 95% CI 0.64-0.73). A clinical prediction model using 8 predictors estimated the absolute 3-year risk of MACE after carotid endarterectomy with a C statistic of 0.69 (95% CI 0.64-0.73).
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