Key result
Elevated resting heart rate (> 80-85 beats/min) is a powerful predictor of cardiovascular morbidity and mortality, independent of other risk factors for atherosclerosis.
Why the study?
Does elevated resting heart rate increase the risk of cardiovascular diseases and mortality in asymptomatic individuals and patients with cardiovascular diseases?
Does elevated resting heart rate increase the risk of cardiovascular diseases and mortality in asymptomatic individuals and patients with cardiovascular diseases?
Elevated resting heart rate (>80-85 bpm) is an independent risk factor for the development of atherosclerosis and cardiovascular events, suggesting it should be considered a major risk factor for ischemic heart disease.
The results of clinical trials have proved that elevated heart rate (> 80-85 beats/min) at rest is directly related to the risk of arterial hypertension and atherosclerosis development, and it is a powerful predictor of cardiovascular morbidity and mortality. Epidemiological studies have shown that these relationships are independent of other risk factors of atherosclerosis and are present in asymptomatic individuals as well as in patients with cardiovascular diseases. The results of experimental and clinical studies suggest that hemodynamic changes due to elevated heart rate have a direct influence on the arterial wall, favouring the development of atherosclerotic lesions. Moreover, heart rate is directly related to the development of cardiovascular events associated with atherosclerotic plaque disruption. Based on these data we believe that heart rate should be listed among major risk factors for ischemic heart disease
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Svistunov et al. (2008) conducted a review in Cardiovascular diseases. Elevated resting heart rate (> 80-85 beats/min) was evaluated on Cardiovascular morbidity and mortality. Elevated resting heart rate (> 80-85 beats/min) is a powerful predictor of cardiovascular morbidity and mortality, independent of other risk factors for atherosclerosis.
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