Why the study?
What is the response of plasma renin activity to orally administered furosemide in unselected hypertensive patients?
Population
100 unselected hypertensive patients
Design
Cross-sectional
Authors
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Suppressed PRA after furosemide is common, especially in Black hypertensives; hypothesis-generating for renin subtyping but should not yet change practice.
What is the response of plasma renin activity to orally administered furosemide in unselected hypertensive patients?
A significant proportion of hypertensive patients, particularly Black patients, exhibit suppressed plasma renin activity in response to furosemide.
Bertram J. Channick (1969) studied this question.
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