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June 6, 2026Journal of Radioanalytical and Nuclear ChemistryOpen Access

Experimental evaluation of 47Sc production by neutron irradiation of metallic titanium at the IEA-R1 research reactor

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Authors

LBLilian Ninoska Muriel BraguinIRIberê Souza RibeiroGPGustavo Seiji Pó

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Overview

Experimental evaluation demonstrates feasibility of producing Sc-47 from titanium, suggesting cost-effective methods for radiopharmaceutical applications.

Key Points

  • This work aims to investigate the feasibility of producing Sc-47 through neutron irradiation of metallic titanium.
  • Neutron irradiation performed at IEA-R1 research reactor.
  • Radionuclide production quantified using high-resolution gamma-ray spectrometry.
  • Experimentally measured specific activities of Sc-47 up to 6.6 MBq g⁻¹.
  • Sc-47 constituted approximately 65% of total activity after two days of decay.
  • Successful demonstration of reactor-based production of Sc-47 from natural titanium.

Cite This Study

Braguin et al. (2026) studied this question.

synapsesocial.com/papers/6a23bc5171a5da9775e77a8fhttps://doi.org/10.1007/s10967-026-10936-7
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Proton-induced reactions for 47Sc (and 46Sc) production: new nuclear cross section measurements on enriched titanium targets2024 · 2 citations
  2. 2Endorsing Titanium–Scandium Radionuclide Generator for PET and Positronium Imaging2026
  3. 347Sc production for medical applications: cross-section optimization with genetic algorithms2025
  4. 4Energy dependent production and radionuclidic purity of $$\:{\:}^{47}\mathbf{S}\mathbf{c}\:$$from $$\:{\:}^{48}\mathbf{C}\mathbf{a}(\varvec{p},\varvec{x}\varvec{n})\:$$reactions: a combined theoretical and data from EXFOR library using the EMPIRE code2026
  5. 5Investigation of 44ti (N, P) and44 Ti (D, 2p) Reactions in the Production of 44sc for Theranostic Applications2025