Key result
Systematic imaging and biomarker monitoring improves management of CTRCD to optimize cardiovascular health.
Why the study?
Cardiovascular toxicity is an increasingly significant side effect of anticancer treatments, and cancer therapy-related cardiac dysfunction requires effective strategies for prediction, monitoring, and management.
Systematic Review
This paper provides a comprehensive overview of cardio-oncology monitoring strategies using imaging and biomarkers, emphasizing the application of 2022 ESC guidelines and the need for prospective data in the Korean population.
Cardio-oncology is a critical field due to the escalating significance of cardiovascular toxicity as a side effect of anticancer treatments. Cancer therapy-related cardiac dysfunction (CTRCD) is a prevalent condition associated with cardiovascular toxicity, necessitating effective strategies for prediction, monitoring, management, and tracking. This comprehensive review examines the definition and risk stratification of CTRCD, explores monitoring approaches during anticancer therapy, and highlights specific cardiovascular toxicities linked to various cancer treatments. These include anthracyclines, HER2-targeted agents, vascular endothelial growth factor inhibitors, immune checkpoint inhibitors, chimeric antigen receptor T-cell therapies, and tumor-infiltrating lymphocytes therapies. Incorporating the Korean data, this review offers insights into the regional nuances in managing CTRCD. Using systematic follow-up incorporating cardiovascular imaging and biomarkers, a better understanding and management of CTRCD can be achieved, optimizing the cardiovascular health of both cancer patients and survivors.
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Cho et al. (2024) conducted a systematic review in Cancer therapy-related cardiac dysfunction (CTRCD). Cardiovascular imaging and biomarkers was evaluated. Systematic follow-up incorporating cardiovascular imaging and biomarkers enables better understanding and management of cancer therapy-related cardiac dysfunction to optimize cardiovascular health.
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