Why the study?
Does hypoxia alter limb blood flow, cardiac output, and O2 uptake during dynamic knee-extensor exercise in healthy young men?
Population
8 healthy young men (aged 21-30 yr) with varying training status (VO2max 41-70 ml/kg/min)
Comparison
Two-legged dynamic knee-extensor exercise under… vs Two-legged dynamic knee-extensor exercise under…
Design
Other, The three experimental conditions were performed in random order
Authors
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Compensatory LBF increases during hypoxic exercise are workload-dependent; leaves open translation to clinical cardiopulmonary disease.
Does hypoxia alter limb blood flow, cardiac output, and O2 uptake during dynamic knee-extensor exercise in healthy young men?
During dynamic exercise in hypoxia, limb blood flow increases to compensate for hypoxemia at submaximal workloads, but this compensatory vasodilation does not occur at peak effort despite available cardiac capacity.
Koskolou et al. (1997) studied this question.