Key result
Right ventricular outflow tract pacing resulted in shorter QRS duration compared with apical pacing (120.9 vs 154.1, P<0.05) and improved regional left ventricular performance at 12 months.
Why the study?
Does right ventricular outflow tract (RVOT) pacing improve left ventricular function and regional wall motion compared to right ventricular apical (RVA) pacing in patients with AV block and normal ejection fraction?
RCT (n=60)
Does right ventricular outflow tract (RVOT) pacing improve left ventricular function and regional wall motion compared to right ventricular apical (RVA) pacing in patients with AV block and normal ejection fraction?
Absolute Event Rate: 120.9% vs 154.1%
p-value: p=<0.05
RVOT pacing may preserve regional left ventricular performance and reduce electromechanical delay better than traditional RVA pacing in patients with AV block.
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Supports RVOT over apical pacing for shorter QRS and regional LV performance in AV block with normal EF; extends small RCT data without global EF benefit.
Wang et al. (2011) conducted an RCT in Atrio-ventricular (AV) block with normal ejection fraction (n=60). Right ventricular outflow tract (RVOT) pacing vs. Right ventricular apical (RVA) pacing was evaluated on QRS duration (p=<0.05). Right ventricular outflow tract pacing resulted in shorter QRS duration compared with apical pacing (120.9 vs 154.1, P<0.05) and improved regional left ventricular performance at 12 months.
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