Key result
TPM 3 is expressed in murine slow-twitch skeletal muscle, accounting for ~31% of total striated tropomyosin, but is absent in fast-twitch musculature and developmental stages of murine hearts.
Authors
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TPM3 isoform mapping in mice leaves open cardiac roles in humans; extends skeletal muscle characterization but should not yet change practice.
Pieples et al. (2000) studied this question. Tropomyosin 3 (TPM 3) expression was evaluated on TPM 3 expression and distribution in murine muscle. TPM 3 is expressed in murine slow-twitch skeletal muscle, accounting for ~31% of total striated tropomyosin, but is absent in fast-twitch musculature and developmental stages of murine hearts.
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